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Index > Protein center > Abcb4(Gene name) > Mouse
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  • Abcb4 (Gene name),
  • Multidrug resistance protein 2 (Protein name ),  MDR2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Abcb4(Mdr2;Pgy-2;Pgy2);
    Protein name:
    Multidrug resistance protein 2;
    Alternative:
    P-glycoprotein 2;ATP-binding cassette sub-family B member 4;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with HAX1.
    Function:
    Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. Mouse MDR2 is not capable of conferring drug resistance.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1276
    Sequence:
    50:
    MDLEAARNGT | ARRLDGDFEL | GSISNQGREK | KKKVNLIGLL | TLFRYSDWQD | 
    100:
    KLFMFLGTLM | AIAHGSGLPL | MMIVFGEMTD | KFVDNTGNFS | LPVNFSLSML | 
    150:
    NPGRILEEEM | TRYAYYYSGL | GGGVLVAAYI | QVSFWTLAAG | RQIKKIRQKF | 
    200:
    FHAILRQEMG | WFDIKGTTEL | NTRLTDDVSK | ISEGIGDKVG | MFFQAIATFF | 
    250:
    AGFIVGFIRG | WKLTLVIMAI | SPILGLSTAV | WAKILSTFSD | KELAAYAKAG | 
    300:
    AVAEEALGAI | RTVIAFGGQN | KELERYQKHL | ENAKKIGIKK | AISANISMGI | 
    350:
    AFLLIYASYA | LAFWYGSTLV | ISKEYTIGNA | MTVFFSILIG | AFSVGQAAPC | 
    400:
    IDAFANARGA | AYVIFDIIDN | NPKIDSFSER | GHKPDNIKGN | LEFSDVHFSY | 
    450:
    PSRANIKILK | GLNLKVKSGQ | TVALVGNSGC | GKSTTVQLLQ | RLYDPTEGKI | 
    500:
    SIDGQDIRNF | NVRCLREIIG | VVSQEPVLFS | TTIAENIRYG | RGNVTMDEIE | 
    550:
    KAVKEANAYD | FIMKLPQKFD | TLVGDRGAQL | SGGQKQRIAI | ARALVRNPKI | 
    600:
    LLLDEATSAL | DTESEAEVQA | ALDKAREGRT | TIVIAHRLST | IRNADVIAGF | 
    650:
    EDGVIVEQGS | HSELMKKEGI | YFRLVNMQTA | GSQILSEEFE | VELSDEKAAG | 
    700:
    DVAPNGWKAR | IFRNSTKKSL | KSPHQNRLDE | ETNELDANVP | PVSFLKVLKL | 
    750:
    NKTEWPYFVV | GTVCAIANGA | LQPAFSIILS | EMIAIFGPGD | DAVKQQKCNM | 
    800:
    FSLVFLGLGV | LSFFTFFLQG | FTFGKAGEIL | TTRLRSMAFK | AMLRQDMSWF | 
    850:
    DDHKNSTGAL | STRLATDAAQ | VQGATGTRLA | LIAQNTANLG | TGIIISFIYG | 
    900:
    WQLTLLLLSV | VPFIAVAGIV | EMKMLAGNAK | RDKKEMEAAG | KIATEAIENI | 
    950:
    RTVVSLTQER | KFESMYVEKL | HGPYRNSVRK | AHIYGITFSI | SQAFMYFSYA | 
    1000:
    GCFRFGSYLI | VNGHMRFKDV | ILVFSAIVLG | AVALGHASSF | APDYAKAKLS | 
    1050:
    AAYLFSLFER | QPLIDSYSGE | GLWPDKFEGS | VTFNEVVFNY | PTRANVPVLQ | 
    1100:
    GLSLEVKKGQ | TLALVGSSGC | GKSTVVQLLE | RFYDPMAGSV | LLDGQEAKKL | 
    1150:
    NVQWLRAQLG | IVSQEPILFD | CSIAENIAYG | DNSRVVPHDE | IVRAAKEANI | 
    1200:
    HPFIETLPQK | YNTRVGDKGT | QLSGGQKQRI | AIARALIRQP | RVLLLDEATS | 
    1250:
    ALDTESEKVV | QEALDKAREG | RTCIVIAHRL | STIQNADLIV | VIENGKVKEH | 
    1276:
    GTHQQLLAQK | GIYFSMVNIQ | AGTQNL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Multidrug resistance protein 2
    Cat.:
    E10409h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Multidrug resistance protein 2
    Cat.:
    E10409m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Multidrug resistance protein 2
    Cat.:
    E10409r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Multidrug resistance protein 2
    Cat.:
    U10409m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Multidrug resistance protein 2
    Cat.:
    U10409h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Multidrug resistance protein 2
    Cat.:
    U10409r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Multidrug resistance protein 2
    Cat.:
    P10409Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Multidrug resistance protein 2
    Polyclonal Antibody for Mouse Multidrug resistance protein 2
    Monoclonal Antibody for Mouse Multidrug resistance protein 2
    Monoclonal Antibody for Mouse Multidrug resistance protein 2
    Monoclonal Antibody for Mouse Multidrug resistance protein 2
    Protein for Mouse Multidrug resistance protein 2
    Protein for Mouse Multidrug resistance protein 2
    Protein for Mouse Multidrug resistance protein 2

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.9%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤8.7%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery

    Recovery was determined by spiking various levels of ABCB4 into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    100

    97-108

    Plasma

    99

    95-106

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ABCB4 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    94-105%

    95-103%

    96-105%

    92-109%

    EDTA plasma(n=5)

    93-105%

    92-107%

    95-103%

    93-106%

    heparin plasma(n=5)

    94-104%

     

    91-105%

    92-108%

    91-109%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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